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In its invasive hyphal form, Candida penetrates the intestinal epithelium and releases more than 70 identified mycotoxins including acetaldehyde, gliotoxin, and candidalysin that trigger systemic inflammation, impair mitochondrial function, disrupt neurotransmitter synthesis, and compromise the integrity of the gut barrier, producing a multi-system clinical presentation that spans gastrointestinal, neurological, endocrine, dermatological, and immunological domains
The two degradation pathways coexist and operate independently of one another, and have therefore distinct physiological significance and regulation
LAC is, therefore, a promising treatment option in patients with diabetic neuropathy